Mob2 Insufficiency Disrupts Neuronal Migration in the Developing Cortex

Mob2 Insufficiency Disrupts Neuronal Migration in the Developing Cortex

Disorders of neuronal mispositioning during brain development are phenotypically heterogeneous and their genetic causes remain largely unknown. Here, we report biallelic variants in a Hippo signaling factor—MOB2—in a patient with one such disorder, periventricular nodular heterotopia (PH). Genetic a...

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Bibliographic Details
Main Authors: O’Neill, Adam C., Kyrousi, Christina, Einsiedler, Melanie, Burtscher, Ingo, Drukker, Micha, Markie, David M., Kirk, Edwin P., Götz, Magdalena, Robertson, Stephen P., Cappello, Silvia
Format: Text
Language:English
Published: Frontiers Media S.A. 2018
Subjects:
Neuroscience
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC5857600/
https://pubmed.ncbi.nlm.nih.gov/29593499
http://dx.doi.org/10.3389/fncel.2018.00057
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https://pmc.ncbi.nlm.nih.gov/articles/PMC5857600/
https://pubmed.ncbi.nlm.nih.gov/29593499
http://dx.doi.org/10.3389/fncel.2018.00057

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