Measurement of tissue azithromycin levels in self-collected vaginal swabs post treatment using liquid chromatography and tandem mass spectrometry (LC-MS/MS)

Measurement of tissue azithromycin levels in self-collected vaginal swabs post treatment using liquid chromatography and tandem mass spectrometry (LC-MS/MS)

BACKGROUND: Azithromycin is recommended for the treatment of uncomplicated urogenital chlamydia infection although the standard 1gram dose sometimes fails to eradicate the infection (treatment failure). One hypothesis proposed for treatment failure has been insufficient levels of the antibiotic at t...

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Main Authors: Vodstrcil, Lenka A., Rupasinghe, Thusitha W. T., Kong, Fabian Y. S., Tull, Dedreia, Worthington, Karen, Chen, Marcus Y., Huston, Wilhelmina M., Timms, Peter, McConville, Malcolm J., Fairley, Christopher K., Bradshaw, Catriona S., Tabrizi, Sepehr N., Hocking, Jane S.
Format: Text
Language:English
Published: Public Library of Science 2017
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Research Article
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC5428968/
https://pubmed.ncbi.nlm.nih.gov/28498845
http://dx.doi.org/10.1371/journal.pone.0177615
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https://pmc.ncbi.nlm.nih.gov/articles/PMC5428968/
https://pubmed.ncbi.nlm.nih.gov/28498845
http://dx.doi.org/10.1371/journal.pone.0177615

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