Super-enhancer-mediated RNA processing revealed by integrative microRNA network analysis
Super-enhancers are an emerging sub-class of regulatory regions controlling cell identity and disease genes. However, their biological function and impact on miRNA networks are unclear. Here we report that super-enhancers drive the biogenesis of master miRNAs crucial for cell identity by enhancing b...
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Main Authors: | , , |
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Format: | Text |
Language: | English |
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2017
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Online Access: | https://pmc.ncbi.nlm.nih.gov/articles/PMC5350633/ https://pubmed.ncbi.nlm.nih.gov/28283057 http://dx.doi.org/10.1016/j.cell.2017.02.015 |
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