Systematic Discovery of Complex Indels in Human Cancers

Systematic Discovery of Complex Indels in Human Cancers

Complex indels are formed by simultaneously deleting and inserting DNA fragments of different sizes at a common genomic location. Here, we present a systematic analysis of somatic complex indels in the coding sequences of over 8,000 cancer cases using Pindel-C. We discovered 285 complex indels in ca...

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Main Authors: Ye, Kai, Wang, Jiayin, Jayasinghe, Reyka, Lameijer, Eric-Wubbo, McMichael, Joshua F., Ning, Jie, McLellan, Michael D., Xie, Mingchao, Cao, Song, Yellapantula, Venkata, Huang, Kuan-lin, Scott, Adam, Foltz, Steven, Niu, Beifang, Johnson, Kimberly J., Moed, Matthijs, Slagboom, P. Eline, Chen, Feng, Wendl, Michael C., Ding, Li
Format: Text
Language:English
Published: 2015
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Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC5003782/
https://pubmed.ncbi.nlm.nih.gov/26657142
http://dx.doi.org/10.1038/nm.4002
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https://pmc.ncbi.nlm.nih.gov/articles/PMC5003782/
https://pubmed.ncbi.nlm.nih.gov/26657142
http://dx.doi.org/10.1038/nm.4002

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