Doxorubicin induced heart failure: Phenotype and molecular mechanisms
Long term survival of childhood cancers is now more than 70%. Anthracyclines, including doxorubicin, are some of the most efficacious anticancer drugs available. However, its use as a chemotherapeutic agent is severely hindered by its dose-limiting toxicities. Most notably observed is cardiotoxicity...
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Main Authors: | , |
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Format: | Text |
Language: | English |
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Elsevier
2015
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Online Access: | https://pmc.ncbi.nlm.nih.gov/articles/PMC4871279/ https://pubmed.ncbi.nlm.nih.gov/27213178 http://dx.doi.org/10.1016/j.ijcha.2015.11.004 |
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