Doxorubicin induced heart failure: Phenotype and molecular mechanisms

Long term survival of childhood cancers is now more than 70%. Anthracyclines, including doxorubicin, are some of the most efficacious anticancer drugs available. However, its use as a chemotherapeutic agent is severely hindered by its dose-limiting toxicities. Most notably observed is cardiotoxicity...

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Bibliographic Details
Main Authors: Mitry, Maria A., Edwards, John G.
Format: Text
Language:English
Published: Elsevier 2015
Subjects:
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC4871279/
https://pubmed.ncbi.nlm.nih.gov/27213178
http://dx.doi.org/10.1016/j.ijcha.2015.11.004
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