A role of uridylation pathway for blockade of let-7 microRNA biogenesis by Lin28B
The precise control of microRNA (miRNA) biosynthesis is crucial for gene regulation. Lin28A and Lin28B are selective inhibitors of biogenesis of let-7 miRNAs involved in development and tumorigenesis. Lin28A selectively inhibits let-7 biogenesis through cytoplasmic uridylation of precursor let-7 by...
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| Main Authors: | , , |
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| Format: | Text |
| Language: | English |
| Published: |
John Wiley & Sons, Ltd
2015
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| Subjects: | |
| Online Access: | https://pmc.ncbi.nlm.nih.gov/articles/PMC4582986/ https://pubmed.ncbi.nlm.nih.gov/26080928 http://dx.doi.org/10.1111/cas.12721 |
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