Quantification of Mitochondrial DNA (mtDNA) Damage and Error Rates by Real-time QPCR

Mitochondrial dysfunction has reported in several diseases including diabetes, cancer, skeletal muscle disorders and neurodegenerative diseases such as Wolfram syndrome. Several different methods have evolved to study mtDNA damage including Southern blotting, 8-oxoG damage, or a comprehensive scanni...

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Bibliographic Details
Main Author: Edwards, John G.
Format: Text
Language:English
Published: 2008
Subjects:
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC4566949/
https://pubmed.ncbi.nlm.nih.gov/19105983
http://dx.doi.org/10.1016/j.mito.2008.11.004
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