Notch1-Dll4 signaling and mechanical force regulate leader cell formation during collective cell migration
At the onset of collective cell migration, a subset of cells within an initially homogenous population acquires a distinct “leader” phenotype with characteristic morphology and motility. However, the factors driving leader cell formation as well as the mechanisms regulating leader cell density durin...
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Main Authors: | , , , , , |
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Format: | Text |
Language: | English |
Published: |
2015
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Subjects: | |
Online Access: | https://pmc.ncbi.nlm.nih.gov/articles/PMC4380165/ https://pubmed.ncbi.nlm.nih.gov/25766473 http://dx.doi.org/10.1038/ncomms7556 |
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