Deletion of STAT5a/b in Vascular Smooth Muscle Abrogates the Male Bias in Hypoxic Pulmonary Hypertension in Mice: Implications in the Human Disease
Chronic hypoxia typically elicits pulmonary hypertension (PH) in mice with a male-dominant phenotype. There is an opposite-sex bias in human PH, with a higher prevalence in women, but greater survival (the “estrogen paradox”). We investigated the involvement of the STAT5a/b species, previously estab...
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| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Metin |
| Dil: | İngilizce |
| Baskı/Yayın Bilgisi: |
ScholarOne
2015
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| Konular: | |
| Online Erişim: | https://pmc.ncbi.nlm.nih.gov/articles/PMC4365065/ https://pubmed.ncbi.nlm.nih.gov/25470773 http://dx.doi.org/10.2119/molmed.2014.00180 |
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