Hypertensive Renal Injury Is Associated with Gene Variation Affecting Immune Signaling

BACKGROUND: The spontaneously hypertensive rat (SHR) strain exists in lines that contrast strongly in susceptibility to renal injury in hypertension. These inbred lines share common ancestry and only 13% of their genomes arise from different ancestors. METHODS AND RESULTS: We used next gen sequencin...

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Bibliographic Details
Main Authors: Braun, Michael C., Herring, Stacy M., Gokul, Nisha, Monita, Monique, Bell, Rebecca, Zhu, Yaming, Gonzalez-Garay, Manuel L., Wenderfer, Scott E., Doris, Peter A.
Format: Text
Language:English
Published: 2014
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Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC4270933/
https://pubmed.ncbi.nlm.nih.gov/25366137
http://dx.doi.org/10.1161/CIRCGENETICS.114.000533
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