Diversity in the pre-immune immunoglobulin repertoire of SHR lines susceptible and resistant to end organ injury
We used next-generation sequencing to identify IGH genetic variation in two closely related hypertensive rat lines that differ in susceptibility to end-organ disease (SHR-A3 and SHR-B2). The two SHR lines differ extensively at the IGH locus from the rat reference genome sequence (RRGS) and from each...
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| Main Authors: | , , , |
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| Format: | Text |
| Language: | English |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://pmc.ncbi.nlm.nih.gov/articles/PMC4257902/ https://pubmed.ncbi.nlm.nih.gov/25056448 http://dx.doi.org/10.1038/gene.2014.40 |
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