Tumor rejection antigen gp96/grp94 is an ATPase: implications for protein folding and antigen presentation.
Immunization of mice with gp96/grp94 heat shock proteins (HSPs) elicits tumor-specific cellular immunity to the tumors from which gp96 is isolated. However, the cDNA sequence of gp96 is identical among tumors and normal tissues. This raises the question regarding the structural basis of the specific...
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Main Authors: | , |
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Format: | Text |
Language: | English |
Published: |
1993
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Online Access: | https://pmc.ncbi.nlm.nih.gov/articles/PMC413580/ https://pubmed.ncbi.nlm.nih.gov/8344253 |
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