Control of mRNA stability contributes to low levels of nuclear poly(A) binding protein 1 (PABPN1) in skeletal muscle

Control of mRNA stability contributes to low levels of nuclear poly(A) binding protein 1 (PABPN1) in skeletal muscle

BACKGROUND: The nuclear poly(A) binding protein 1 (PABPN1) is a ubiquitously expressed protein that plays critical roles at multiple steps in post-transcriptional regulation of gene expression. Short expansions of the polyalanine tract in the N-terminus of PABPN1 lead to oculopharyngeal muscular dys...

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Bibliographic Details
Main Authors: Apponi, Luciano H, Corbett, Anita H, Pavlath, Grace K
Format: Text
Language:English
Published: BioMed Central 2013
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Research
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC3879409/
https://pubmed.ncbi.nlm.nih.gov/24083404
http://dx.doi.org/10.1186/2044-5040-3-23
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https://pmc.ncbi.nlm.nih.gov/articles/PMC3879409/
https://pubmed.ncbi.nlm.nih.gov/24083404
http://dx.doi.org/10.1186/2044-5040-3-23

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