Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif

Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif

MicroRNAs modulate tumorigenesis through suppression of specific genes. As many tumour types rely on overlapping oncogenic pathways, a core set of microRNAs may exist, which consistently drives or suppresses tumorigenesis in many cancer types. Here we integrate The Cancer Genome Atlas (TCGA) pan-can...

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Main Authors: Hamilton, Mark P., Rajapakshe, Kimal, Hartig, Sean M., Reva, Boris, McLellan, Michael D., Kandoth, Cyriac, Ding, Li, Zack, Travis I., Gunaratne, Preethi H., Wheeler, David A., Coarfa, Cristian, McGuire, Sean E.
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Language:English
Published: Nature Pub. Group 2013
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Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC3868236/
https://pubmed.ncbi.nlm.nih.gov/24220575
http://dx.doi.org/10.1038/ncomms3730
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https://pmc.ncbi.nlm.nih.gov/articles/PMC3868236/
https://pubmed.ncbi.nlm.nih.gov/24220575
http://dx.doi.org/10.1038/ncomms3730

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