MUC1* Ligand, NM23-H1, Is a Novel Growth Factor That Maintains Human Stem Cells in a More Naïve State

MUC1* Ligand, NM23-H1, Is a Novel Growth Factor That Maintains Human Stem Cells in a More Naïve State

We report that a single growth factor, NM23-H1, enables serial passaging of both human ES and iPS cells in the absence of feeder cells, their conditioned media or bFGF in a fully defined xeno-free media on a novel defined, xeno-free surface. Stem cells cultured in this system show a gene expression...

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Main Authors: Smagghe, Benoit J., Stewart, Andrew K., Carter, Mark G., Shelton, Laura M., Bernier, Kyle J., Hartman, Eric J., Calhoun, Amy K., Hatziioannou, Vasilios M., Lillacci, Gabriele, Kirk, Brian A., DiNardo, Brian A., Kosik, Kenneth S., Bamdad, Cynthia
Format: Text
Language:English
Published: Public Library of Science 2013
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Research Article
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC3591366/
https://pubmed.ncbi.nlm.nih.gov/23505541
http://dx.doi.org/10.1371/journal.pone.0058601
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https://pmc.ncbi.nlm.nih.gov/articles/PMC3591366/
https://pubmed.ncbi.nlm.nih.gov/23505541
http://dx.doi.org/10.1371/journal.pone.0058601

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