ACTN3 Allele Frequency in Humans Covaries with Global Latitudinal Gradient
A premature stop codon in ACTN3 resulting in α-actinin-3 deficiency (the ACTN3 577XX genotype) is common in humans and reduces strength, muscle mass, and fast-twitch fiber diameter, but increases the metabolic efficiency of skeletal muscle. Linkage disequilibrium data suggest that the ACTN3 R577X al...
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Main Authors: | , , , , , , |
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Format: | Text |
Language: | English |
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Public Library of Science
2013
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Online Access: | https://pmc.ncbi.nlm.nih.gov/articles/PMC3554748/ https://pubmed.ncbi.nlm.nih.gov/23359641 http://dx.doi.org/10.1371/journal.pone.0052282 |
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