Predicting the effects of frameshifting indels
Each human has approximately 50 to 280 frameshifting indels, yet their implications are unknown. We created SIFT Indel, a prediction method for frameshifting indels that has 84% accuracy. The percentage of human frameshifting indels predicted to be gene-damaging is negatively correlated with allele...
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Main Authors: | , |
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Format: | Text |
Language: | English |
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BioMed Central
2012
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Online Access: | https://pmc.ncbi.nlm.nih.gov/articles/PMC3334572/ https://pubmed.ncbi.nlm.nih.gov/22322200 http://dx.doi.org/10.1186/gb-2012-13-2-r9 |
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