Predicting the effects of frameshifting indels

Each human has approximately 50 to 280 frameshifting indels, yet their implications are unknown. We created SIFT Indel, a prediction method for frameshifting indels that has 84% accuracy. The percentage of human frameshifting indels predicted to be gene-damaging is negatively correlated with allele...

Full description

Saved in:
Bibliographic Details
Main Authors: Hu, Jing, Ng, Pauline C
Format: Text
Language:English
Published: BioMed Central 2012
Subjects:
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC3334572/
https://pubmed.ncbi.nlm.nih.gov/22322200
http://dx.doi.org/10.1186/gb-2012-13-2-r9
Tags: Add Tag
No Tags, Be the first to tag this record!