Breast and ovarian cancer risk evaluation in families with a disease-causing mutation in BRCA1/2

Germline mutations in BRCA1 and BRCA2 confer high risks of breast and ovarian cancer, and their identification allows genetic testing of at-risk relatives. However, estimates of these risks illustrate controversies, depending on the published series. The penetrance, the earlier onset of the disease...

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Bibliographic Details
Main Authors: Beristain, Elena, Ibáñez, Berta, Vergara, Itziar, Martínez-Bouzas, Cristina, Guerra, Isabel, Tejada, Maria Isabel
Format: Text
Language:English
Published: Springer-Verlag 2010
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Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC3185985/
https://pubmed.ncbi.nlm.nih.gov/22460208
http://dx.doi.org/10.1007/s12687-010-0014-0
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