Predicting Deleterious Amino Acid Substitutions
Many missense substitutions are identified in single nucleotide polymorphism (SNP) data and large-scale random mutagenesis projects. Each amino acid substitution potentially affects protein function. We have constructed a tool that uses sequence homology to predict whether a substitution affects pro...
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| Main Authors: | , |
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| Format: | Text |
| Language: | English |
| Published: |
Cold Spring Harbor Laboratory Press
2001
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| Subjects: | |
| Online Access: | https://pmc.ncbi.nlm.nih.gov/articles/PMC311071/ https://pubmed.ncbi.nlm.nih.gov/11337480 http://dx.doi.org/10.1101/gr.176601 |
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