Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis

Dishevelled (Dsh) induces a secondary axis and can translocate to the membrane when activated by Frizzleds; however, dominant-negative approaches have not supported a role for Dsh in primary axis formation. We demonstrate that the Dsh protein is post-translationally modified at the dorsal side of th...

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Bibliographic Details
Main Authors: Rothbächer, Ute, Laurent, Micheline N., Deardorff, Matthew A., Klein, Peter S., Cho, Ken W.Y., Fraser, Scott E.
Format: Text
Language:English
Published: Oxford University Press 2000
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Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC305640/
https://pubmed.ncbi.nlm.nih.gov/10698942
http://dx.doi.org/10.1093/emboj/19.5.1010
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