A multi-centre randomised phase III trial of Dexamethasone vs Dexamethasone and diethylstilbestrol in castration-resistant prostate cancer: immediate vs deferred Diethylstilbestrol

BACKGROUND: The role of further hormone therapy in castration-resistant prostate cancer (CRPC) remains unclear. We performed a multi-centre randomised phase III study comparing the use of Dexamethasone, Aspirin, and immediate addition of Diethylstilbestrol (DAiS) vs Dexamethasone, Aspirin, and defer...

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Main Authors: Shamash, J, Powles, T, Sarker, S J, Protheroe, A, Mithal, N, Mills, R, Beard, R, Wilson, P, Tranter, N, O'Brien, N, McFaul, S, Oliver, T
Format: Text
Language:English
Published: Nature Publishing Group 2011
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Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC3049603/
https://pubmed.ncbi.nlm.nih.gov/21285990
http://dx.doi.org/10.1038/bjc.2011.7
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