Mouse Eri1 interacts with the ribosome and catalyzes 5.8S rRNA processing

Mouse Eri1 interacts with the ribosome and catalyzes 5.8S rRNA processing

Eri1 is a 3′-to-5′ exoribonuclease conserved from fission yeast to humans. Here we show that Eri1 associates with ribosomes and ribosomal RNA (rRNA). Ribosomes from Eri1– deficient mice contain 5.8S rRNA that is aberrantly extended at its 3′ end, and Eri1, but not a catalytically inactive mutant, co...

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Main Authors: Ansel, K Mark, Pastor, William A, Rath, Nicola, Lapan, Ariya D, Glasmacher, Elke, Wolf, Christine, Smith, Laura C, Papadopoulou, Nikoletta, Lamperti, Edward D, Tahiliani, Mamta, Ellwart, Joachim W, Shi, Yujiang, Kremmer, Elisabeth, Rao, Anjana, Heissmeyer, Vigo
Format: Text
Language:English
Published: 2008
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Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC3032500/
https://pubmed.ncbi.nlm.nih.gov/18438418
http://dx.doi.org/10.1038/nsmb.1417
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https://pmc.ncbi.nlm.nih.gov/articles/PMC3032500/
https://pubmed.ncbi.nlm.nih.gov/18438418
http://dx.doi.org/10.1038/nsmb.1417

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