Monte Carlo-minimization approach to the multiple-minima problem in protein folding.
A Monte Carlo-minimization method has been developed to overcome the multiple-minima problem. The Metropolis Monte Carlo sampling, assisted by energy minimization, surmounts intervening barriers in moving through successive discrete local minima in the multidimensional energy surface. The method has...
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| Main Authors: | , |
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| Format: | Text |
| Language: | English |
| Published: |
1987
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| Subjects: | |
| Online Access: | https://pmc.ncbi.nlm.nih.gov/articles/PMC299132/ https://pubmed.ncbi.nlm.nih.gov/3477791 |
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