Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins

Adiponutrin (PNPLA3) is a predominantly liver-expressed transmembrane protein with phospholipase activity that is regulated by fasting and feeding. Recent genome-wide association studies identified PNPLA3 to be associated with hepatic fat content and liver function, thus pointing to a possible invol...

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Main Authors: Kollerits, Barbara, Coassin, Stefan, Beckmann, Noam D., Teumer, Alexander, Kiechl, Stefan, Döring, Angela, Kavousi, Maryam, Hunt, Steven C., Lamina, Claudia, Paulweber, Bernhard, Kutalik, Zoltán, Nauck, Matthias, van Duijn, Cornelia M., Heid, Iris M., Willeit, Johann, Brandstätter, Anita, Adams, Ted D., Mooser, Vincent, Aulchenko, Yurii S., Völzke, Henry, Kronenberg, Florian
Format: Text
Language:English
Published: Oxford University Press 2009
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Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC2773273/
https://pubmed.ncbi.nlm.nih.gov/19729411
http://dx.doi.org/10.1093/hmg/ddp424
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