Mechanisms for human genomic rearrangements

Genomic rearrangements describe gross DNA changes of the size ranging from a couple of hundred base pairs, the size of an average exon, to megabases (Mb). When greater than 3 to 5 Mb, such changes are usually visible microscopically by chromosome studies. Human diseases that result from genomic rear...

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Bibliographic Details
Main Authors: Gu, Wenli, Zhang, Feng, Lupski, James R
Format: Text
Language:English
Published: BioMed Central 2008
Subjects:
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC2583991/
https://pubmed.ncbi.nlm.nih.gov/19014668
http://dx.doi.org/10.1186/1755-8417-1-4
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