Copy number variation at the breakpoint region of isochromosome 17q

Isochromosome 17q, or i(17q), is one of the most frequent nonrandom changes occurring in human neoplasia. Most of the i(17q) breakpoints cluster within a ∼240-kb interval located in the Smith-Magenis syndrome common deletion region in 17p11.2. The breakpoint cluster region is characterized by a comp...

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Bibliographic Details
Main Authors: Carvalho, Claudia M.B., Lupski, James R.
Format: Text
Language:English
Published: Cold Spring Harbor Laboratory Press 2008
Subjects:
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC2577857/
https://pubmed.ncbi.nlm.nih.gov/18714090
http://dx.doi.org/10.1101/gr.080697.108
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