Array‐CGH detection of micro rearrangements in mentally retarded individuals: clinical significance of imbalances present both in affected children and normal parents

Array‐CGH detection of micro rearrangements in mentally retarded individuals: clinical significance of imbalances present both in affected children and normal parents

BACKGROUND: The underlying causes of mental retardation remain unknown in about half the cases. Recent array‐CGH studies demonstrated cryptic imbalances in about 25% of patients previously thought to be chromosomally normal. OBJECTIVE AND METHODS: Array‐CGH with approximately 3500 large insert clone...

Full description

Saved in:
Bibliographic Details
Main Authors: Rosenberg, C, Knijnenburg, J, Bakker, E, Vianna‐Morgante, A M, Sloos, W, Otto, P A, Kriek, M, Hansson, K, Krepischi‐Santos, A C V, Fiegler, H, Carter, N P, Bijlsma, E K, van Haeringen, A, Szuhai, K, Tanke, H J
Format: Text
Language:English
Published: BMJ Group 2006
Subjects:
Letter to JMG
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC2564641/
https://pubmed.ncbi.nlm.nih.gov/15980116
http://dx.doi.org/10.1136/jmg.2005.032268
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://pmc.ncbi.nlm.nih.gov/articles/PMC2564641/
https://pubmed.ncbi.nlm.nih.gov/15980116
http://dx.doi.org/10.1136/jmg.2005.032268

Similar Items