Transforming growth factor β targeted inactivation of cyclin E:cyclin-dependent kinase 2 (Cdk2) complexes by inhibition of Cdk2 activating kinase activity
Transforming growth factor β (TGF-β)-mediated G(1) arrest previously has been shown to specifically target inactivation of cyclin D:cyclin-dependent kinase (Cdk) 4/6 complexes. We report here that TGF-β-treated human HepG2 hepatocellular carcinoma cells arrest in G(1), but retain continued cyclin D:...
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| Main Authors: | , , , , , |
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| 格式: | Text |
| 語言: | 英语 |
| 出版: |
The National Academy of Sciences
1999
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| 主題: | |
| 在線閱讀: | https://pmc.ncbi.nlm.nih.gov/articles/PMC24755/ https://pubmed.ncbi.nlm.nih.gov/10611320 |
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