Pyrrolidine Dithiocarbamate Restores Endothelial Cell Membrane Integrity and Attenuates Monocrotaline-Induced Pulmonary Artery Hypertension

Pyrrolidine Dithiocarbamate Restores Endothelial Cell Membrane Integrity and Attenuates Monocrotaline-Induced Pulmonary Artery Hypertension

Monocrotaline (MCT)-induced pulmonary artery hypertension (PAH) in rats is preceded by an inflammatory response, progressive endothelial cell membrane disruption, reduction in the expression of caveolin-1 and reciprocal activation of STAT3 (PY-STAT3). Superoxide and NF-κB have been implicated in PAH...

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Bibliografische gegevens
Hoofdauteurs: Huang, Jing, Kaminski, Pawel M., Edwards, John G., Yeh, Albert, Wolin, Michael S., Frishman, William H., Gewitz, Michael H., Mathew, Rajamma
Formaat: Text
Taal:Engels
Gepubliceerd in: 2008
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Article
Online toegang:https://pmc.ncbi.nlm.nih.gov/articles/PMC2441448/
https://pubmed.ncbi.nlm.nih.gov/18390833
http://dx.doi.org/10.1152/ajplung.00069.2007
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Internet

https://pmc.ncbi.nlm.nih.gov/articles/PMC2441448/
https://pubmed.ncbi.nlm.nih.gov/18390833
http://dx.doi.org/10.1152/ajplung.00069.2007

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