Encapsulation into sterically stabilised liposomes enhances the immunogenicity of melanoma-associated Melan-A/MART-1 epitopes

Encapsulation into sterically stabilised liposomes enhances the immunogenicity of melanoma-associated Melan-A/MART-1 epitopes

Tumour-associated antigens (TAA)-specific vaccination requires highly immunogenic reagents capable of inducing cytotoxic T cells (CTL). Soluble peptides are currently used in clinical applications despite an acknowledged poor immunogenicity. Encapsulation into liposomes has been suggested to improve...

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Main Authors: Adamina, M, Bolli, M, Albo, F, Cavazza, A, Zajac, P, Padovan, E, Schumacher, R, Reschner, A, Feder, C, Marti, W R, Oertli, D, Heberer, M, Spagnoli, G C
Format: Text
Language:English
Published: Nature Publishing Group 2004
Subjects:
Experimental Therapeutics
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC2395333/
https://pubmed.ncbi.nlm.nih.gov/14710238
http://dx.doi.org/10.1038/sj.bjc.6601473
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https://pmc.ncbi.nlm.nih.gov/articles/PMC2395333/
https://pubmed.ncbi.nlm.nih.gov/14710238
http://dx.doi.org/10.1038/sj.bjc.6601473

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