Effects of muscarinic M2 and M3 receptor stimulation and antagonism on responses to isoprenaline of guinea-pig trachea in vitro.

1. In guinea-pig and canine airway smooth muscle, there is reduced beta-adrenoceptor agonist sensitivity in tissues pre-contracted with muscarinic agonists when compared to tissues pre-contracted with other spasmogens, such as histamine or leukotriene D4. This reduced sensitivity may be the result o...

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Bibliographic Details
Main Authors: Watson, N., Eglen, R. M.
Format: Text
Language:English
Published: 1994
Subjects:
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC1910305/
https://pubmed.ncbi.nlm.nih.gov/8032639
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