Tumor necrosis factor-alpha modulates monocyte/macrophage apoprotein E gene expression.
apo E has been shown to modulate cholesterol balance in arterial wall cells. Production of apo E by macrophages in atherosclerotic plaques could thereby influence the development of the plaque lesion. Cytokines, including TNF alpha, have been identified in human lesions, therefore, we undertook a se...
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Main Authors: | , , |
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Format: | Text |
Language: | English |
Published: |
1995
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Online Access: | https://pmc.ncbi.nlm.nih.gov/articles/PMC185279/ https://pubmed.ncbi.nlm.nih.gov/7635986 |
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