A novel mutation in the tyrosine kinase domain of ERBB2 in hepatocellular carcinoma

BACKGROUND: Several studies showed that gain-of-function somatic mutations affecting the catalytic domain of EGFR in non-small cell lung carcinomas were associated with response to gefitinib and erlotinib, both EGFR-tyrosine kinase inhibitors. In addition, 4% of non-small cell lung carcinomas were s...

Full description

Saved in:
Bibliographic Details
Main Authors: Bekaii-Saab, Tanios, Williams, Nita, Plass, Christoph, Calero, Miguel Villalona, Eng, Charis
Format: Text
Language:English
Published: BioMed Central 2006
Subjects:
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC1712353/
https://pubmed.ncbi.nlm.nih.gov/17150109
http://dx.doi.org/10.1186/1471-2407-6-278
Tags: Add Tag
No Tags, Be the first to tag this record!