A novel mutation in the tyrosine kinase domain of ERBB2 in hepatocellular carcinoma
BACKGROUND: Several studies showed that gain-of-function somatic mutations affecting the catalytic domain of EGFR in non-small cell lung carcinomas were associated with response to gefitinib and erlotinib, both EGFR-tyrosine kinase inhibitors. In addition, 4% of non-small cell lung carcinomas were s...
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Main Authors: | , , , , |
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Format: | Text |
Language: | English |
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BioMed Central
2006
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Subjects: | |
Online Access: | https://pmc.ncbi.nlm.nih.gov/articles/PMC1712353/ https://pubmed.ncbi.nlm.nih.gov/17150109 http://dx.doi.org/10.1186/1471-2407-6-278 |
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