SIFT: predicting amino acid changes that affect protein function

Single nucleotide polymorphism (SNP) studies and random mutagenesis projects identify amino acid substitutions in protein-coding regions. Each substitution has the potential to affect protein function. SIFT (Sorting Intolerant From Tolerant) is a program that predicts whether an amino acid substitut...

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Bibliographic Details
Main Authors: Ng, Pauline C., Henikoff, Steven
Format: Text
Language:English
Published: Oxford University Press 2003
Subjects:
Online Access:https://pmc.ncbi.nlm.nih.gov/articles/PMC168916/
https://pubmed.ncbi.nlm.nih.gov/12824425
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