Global Individual Ancestry Using Principal Components for Family Data
Studies of complex human diseases and traits associated with candidate genes are potentially vulnerable to bias (confounding) due to population stratification and inbreeding, especially in admixed population. In GWAS, the principal components (PCs) method provides a global ancestry value per subject...
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Auteurs principaux: | , , , |
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Format: | Artigo |
Langue: | anglais |
Publié: |
2015
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Accès en ligne: | https://doi.org/10.1159/000381908 |
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