Vps41 functions as a molecular ruler for HOPS tethering complex function
Fusion at the lysosome (or the yeast vacuole) requires the conserved hexameric HOPS tethering complex. HOPS binds to the vacuolar Rab7-like GTPase Ypt7 via its subunits Vps41 and Vps39 and supports fusion by promoting SNARE assembly. In contrast to its sister complex CORVET, the Ypt7-interacting dom...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2025
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| Online Access: | https://doi.org/10.1242/jcs.263788 |
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