A critical role of N4-acetylation of cytidine in mRNA by NAT10 in T cell expansion and antiviral immunity

A critical role of N4-acetylation of cytidine in mRNA by NAT10 in T cell expansion and antiviral immunity

Following activation, naive T cells exit quiescence and require global translation for rapid expansion, yet the underlying mechanisms remain unclear. Here, we show that during T cell activation, cells upregulate the expression of N-acetyltransferase 10 (NAT10), an enzyme responsible for N4-acetylcyt...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Lu Sun, Xiaoyan Li, Feixiang Xu, Yu‐Wen Chen, Xushuo Li, Zhicheng Yang, Ying Yang, Ke Wang, Tianyi Ren, Zihao Lin, Hua Wang, Xiangdong Wang, Yan Lü, Zhenju Song, Zhou‐Li Cheng, Duojiao Wu
Aineistotyyppi: Artigo
Kieli:englanti
Julkaistu: 2025
Linkit:https://doi.org/10.1038/s41590-025-02100-2
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Internet

https://doi.org/10.1038/s41590-025-02100-2

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