The Plasma Membrane P-Type ATPase CtpA Is Required for Mycobacterium tuberculosis Virulence in Copper-Activated Macrophages in a Mouse Model of Progressive Tuberculosis

Background/Objective: Finding new targets to attenuate Mycobacterium tuberculosis (Mtb) is key in the development of new TB vaccines. In this context, plasma membrane P-type ATPases are relevant for mycobacterial homeostasis and virulence. In this work, we investigate the role of the copper-transpor...

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Main Authors: Marcela López-Ruíz, Jorge Barrios‐Payán, Milena Maya-Hoyos, Rogelio Hernández‐Pando, Marisol Ocampo, Carlos Y. Soto, Dulce Mata‐Espinosa
Formato: Artigo
Idioma:Inglês
Publicado em: 2025
Acesso em linha:https://doi.org/10.3390/biomedicines13020439
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