Phase 2 Study to Evaluate the Efficacy and Safety of Inhaled Nitric Oxide Therapy in Patients With Severe Right Heart Failure Associated With Pulmonary Hypertension ― Protocol for the PHiNO Study ―

Acute right heart failure (RHF) is a syndrome characterized by sudden right ventricular dysfunction leading to systemic hypoperfusion, which carries a poor prognosis, particularly in patients with pulmonary hypertension (PH). Early reduction of pulmonary vascular resistance (PVR) is crucial for impr...

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Main Authors: Jin Ueda, Akihiro Tsuji, Tatsuo Aoki, Ryotaro Asano, Takatoyo Kiko, Hiroya Hayashi, Hiroyuki Endo, Naruhiro Nishi, Ryo Takano, Shinya Fujisaki, Mitsumasa Akao, Koko Asakura, Haruko Yamamoto, Takeshi Ogo
Format: Artigo
Language:English
Published: 2025
Online Access:https://doi.org/10.1253/circrep.cr-24-0125
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