Effect of Lipid Nanoparticle Physico-Chemical Properties and Composition on Their Interaction with the Immune System

Lipid nanoparticles (LNPs) have shown promise as a delivery system for nucleic acid-based therapeutics, including DNA, siRNA, and mRNA vaccines. The immune system plays a critical role in the response to these nanocarriers, with innate immune cells initiating an early response and adaptive immune ce...

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Detalhes bibliográficos
Main Authors: Laura Catenacci, Rachele Rossi, Francesca Sechi, Daniela Buonocore, Milena Sorrenti, Sara Perteghella, Marco Peviani, Maria Cristina Bonferoni
Formato: Revisão
Idioma:Inglês
Publicado em: 2024
Acesso em linha:https://doi.org/10.3390/pharmaceutics16121521
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