A thermosensitive chitosan hydrogel: An attempt for the nasal delivery of dimethyl fumarate
Dimethyl fumarate (DMF) is a drug that is orally administered for the treatment of relapsing-remitting multiple sclerosis. However, DMF causes gastrointestinal side effects and flushing in 43 % of patients, which significantly contributes to treatment discontinuation. To reduce side effects and incr...
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Main Authors: | , , , , , , , , |
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Format: | Artigo |
Language: | English |
Published: |
2024
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Online Access: | https://doi.org/10.1016/j.ijbiomac.2024.134908 |
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