A thermosensitive chitosan hydrogel: An attempt for the nasal delivery of dimethyl fumarate

Dimethyl fumarate (DMF) is a drug that is orally administered for the treatment of relapsing-remitting multiple sclerosis. However, DMF causes gastrointestinal side effects and flushing in 43 % of patients, which significantly contributes to treatment discontinuation. To reduce side effects and incr...

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Bibliographic Details
Main Authors: Noelia Nieto González, Giovanna Rassu, Massimo Cossu, Laura Catenacci, Milena Sorrenti, Eleonora Sofia Cama, Carla Serri, Paolo Giunchedi, Elisabetta Gavini
Format: Artigo
Language:English
Published: 2024
Online Access:https://doi.org/10.1016/j.ijbiomac.2024.134908
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