Cellular senescence in the pathogenesis of pulmonary arterial hypertension: the good, the bad and the uncertain
Senescence refers to a cellular state marked by irreversible cell cycle arrest and the secretion of pro-inflammatory and tissue-remodeling factors. The senescence associated secretory phenotype (SASP) impacts the tissue microenvironment and provides cues for the immune system to eliminate senescent...
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| Hlavní autoři: | , |
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| Médium: | Revisão |
| Jazyk: | angličtina |
| Vydáno: |
2024
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| On-line přístup: | https://doi.org/10.3389/fimmu.2024.1403669 https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1403669/pdf |
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