Cellular senescence in the pathogenesis of pulmonary arterial hypertension: the good, the bad and the uncertain

Senescence refers to a cellular state marked by irreversible cell cycle arrest and the secretion of pro-inflammatory and tissue-remodeling factors. The senescence associated secretory phenotype (SASP) impacts the tissue microenvironment and provides cues for the immune system to eliminate senescent...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Elmira Safaie Qamsari, Duncan J. Stewart
Fformat: Revisão
Iaith:Saesneg
Cyhoeddwyd: 2024
Mynediad Ar-lein:https://doi.org/10.3389/fimmu.2024.1403669
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1403669/pdf
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