Caspase-8 promotes scramblase-mediated phosphatidylserine exposure and fusion of osteoclast precursors
Abstract Efficient cellular fusion of mononuclear precursors is the prerequisite for the generation of fully functional multinucleated bone-resorbing osteoclasts. However, the exact molecular factors and mechanisms controlling osteoclast fusion remain incompletely understood. Here we identify RANKL-...
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Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Sprache: | Englisch |
Veröffentlicht: |
2024
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Online-Zugang: | https://doi.org/10.1038/s41413-024-00338-4 https://www.nature.com/articles/s41413-024-00338-4.pdf |
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