Structure of the endosomal CORVET tethering complex
Abstract Cells depend on their endolysosomal system for nutrient uptake and downregulation of plasma membrane proteins. These processes rely on endosomal maturation, which requires multiple membrane fusion steps. Early endosome fusion is promoted by the Rab5 GTPase and its effector, the hexameric CO...
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Main Authors: | , , , , , , , , |
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Format: | Artigo |
Language: | English |
Published: |
2024
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Online Access: | https://doi.org/10.1038/s41467-024-49137-9 https://www.nature.com/articles/s41467-024-49137-9.pdf |
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