Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes

Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes

Abstract Acute and chronic coronary syndromes (ACS and CCS) are leading causes of mortality. Inflammation is considered a key pathogenic driver of these diseases, but the underlying immune states and their clinical implications remain poorly understood. Multiomic factor analysis (MOFA) allows unsupe...

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Autores principales: Kami Pekayvaz, Corinna Losert, Viktoria Knottenberg, Christoph Gold, Irene V. van Blokland, Roy Oelen, Hilde E. Groot, Jan Walter Benjamins, Sophia Brambs, Rainer Kaiser, Adrian Gottschlich, Gordon Victor Hoffmann, Luke Eivers, Alejandro Martinez-Navarro, Nils Bruns, Susanne Stiller, Sezer Akgöl, Keyang Yue, Vivien Polewka, Raphael Escaig, Markus Joppich, Aleksandar Janjic, Oliver Popp, Sebastian Kobold, Tobias Petzold, Ralf Zimmer, Wolfgang Enard, Kathrin Saar, Philipp Mertins, Norbert Huebner, Pim van der Harst, Lude Franke, Monique G.P. van der Wijst, Steffen Maßberg, Matthias Heinig, Leo Nicolai, Konstantin Stark
Formato: Artigo
Lenguaje:inglés
Publicado: 2024
Acceso en línea:https://doi.org/10.1038/s41591-024-02953-4
https://www.nature.com/articles/s41591-024-02953-4.pdf
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https://doi.org/10.1038/s41591-024-02953-4
https://www.nature.com/articles/s41591-024-02953-4.pdf

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