Molecular Pathways and Cellular Subsets Associated with Adverse Clinical Outcomes in Overlapping Immune-Related Myocarditis and Myositis

Molecular Pathways and Cellular Subsets Associated with Adverse Clinical Outcomes in Overlapping Immune-Related Myocarditis and Myositis

Abstract Immune checkpoint therapies (ICT) can induce life-threatening immune-related adverse events, including myocarditis and myositis, which are rare but often concurrent. The molecular pathways and immune subsets underlying these toxicities remain poorly understood. To address this need, we perf...

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Auteurs principaux: Bilal A. Siddiqui, Nicolas L. Palaskas, Sreyashi Basu, Yibo Dai, Zhong He, Shalini S. Yadav, James P. Allison, Rahul A. Sheth, Sudhakar Tummala, L. Maximilian Buja, Meenakshi B. Bhattacharjee, Cezar Iliescu, Anishia Rawther-Karedath, Anita Deswal, Linghua Wang, Padmanee Sharma, Sumit K. Subudhi
Format: Artigo
Langue:anglais
Publié: 2024
Accès en ligne:https://doi.org/10.1158/2326-6066.cir-24-0011
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https://doi.org/10.1158/2326-6066.cir-24-0011

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