Human amniotic mesenchymal stem cells-derived conditioned medium and exosomes alleviate oxidative stress-induced retinal degeneration by activating PI3K/Akt/FoxO3 pathway

Human amniotic mesenchymal stem cells-derived conditioned medium and exosomes alleviate oxidative stress-induced retinal degeneration by activating PI3K/Akt/FoxO3 pathway

Age-related macular degeneration (AMD) is the leading cause of vision loss among the elderly, which is primarily attributed to oxidative stress-induced damage to the retinal pigment epithelium (RPE). Human amniotic mesenchymal stem cells (hAMSC) were considered to be one of the most promising stem c...

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Główni autorzy: Zhe-Qing Peng, Xiao‐Hui Guan, Zhenping Yu, Jie Wu, Xin‐Hao Han, Minghui Li, Xin-Hui Qu, Zhiping Chen, Xiao‐Jian Han, X. Wang
Format: Artigo
Język:angielski
Wydane: 2024
Dostęp online:https://doi.org/10.1016/j.exer.2024.109919
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https://doi.org/10.1016/j.exer.2024.109919

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