Initiation of a ZAKα-dependent ribotoxic stress response by the innate immunity endoribonuclease RNase L
RNase L is an endoribonuclease of higher vertebrates that functions in antiviral innate immunity. Interferons induce oligoadenylate synthetase enzymes that sense double-stranded RNA of viral origin leading to the synthesis of 2′,5′-oligoadenylate (2-5A) activators of RNase L. However, it is unknown...
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| Hoofdauteurs: | , , , , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Engels |
| Gepubliceerd in: |
2024
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| Online toegang: | https://doi.org/10.1016/j.celrep.2024.113998 https://www.cell.com/article/S2211124724003267/pdf |
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