Bruton's tyrosine kinase inhibition for the treatment of allergic disorders
IgE signaling through its high-affinity receptor FcεRI is central to the pathogenesis of numerous allergic disorders. Oral inhibitors of Bruton's tyrosine kinase (BTKis), which are currently FDA-approved for the treatment of B cell malignancies, broadly inhibit the FcεRI pathway in human mast c...
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主要な著者: | , , |
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フォーマット: | Revisão |
言語: | 英語 |
出版事項: |
2024
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オンライン・アクセス: | https://doi.org/10.1016/j.anai.2024.03.002 |
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