Bruton's tyrosine kinase inhibition for the treatment of allergic disorders

IgE signaling through its high-affinity receptor FcεRI is central to the pathogenesis of numerous allergic disorders. Oral inhibitors of Bruton's tyrosine kinase (BTKis), which are currently FDA-approved for the treatment of B cell malignancies, broadly inhibit the FcεRI pathway in human mast c...

詳細記述

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書誌詳細
主要な著者: Erica V. Lin, Ragha Suresh, Melanie C. Dispenza
フォーマット: Revisão
言語:英語
出版事項: 2024
オンライン・アクセス:https://doi.org/10.1016/j.anai.2024.03.002
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